Table 1 Major vertebrate central nervous tissue
proteoglycans whose cDNA has been cloned.

PG Major GAG Tissue EMBL/Genbank
(source)

Secreted PG
Aggrecan CS/KS brain, cartilage J03485 (rat)
Versican CS brain, mesenchyme X15998 (human)
Neurocan CS brain M97161 (rat)
Brevican* CS brain X87096 (mouse)
Decorin CS/DS brain, connective tissue X59859 (rat)
Biglycan CS/DS brain, connective tissue U17834 (rat)
Testican CS/HS brain, testis X92864 (mouse)
Perlecan HS brain, basement membrane L22078 (human)
Dystroglycan HS brain, muscle X86073 (mouse)
Agrin HS brain, muscle M97371 (chick)
Claustrin KS brain X67778 (chick)
Transmembrane PG
NG2-PG CS brain, cartilage X56541 (rat)
RPTP zeta/beta** CS/KS brain, cartilage U04998 (rat)
Neuroglycan C CS brain U39553 (rat)
Appican CS brain, connective tissue Y00264 (human)
N-syndecan HS brain U73184 (rat)
SV2 KS brain L05435 (rat)
GPI-anchored PG
Glypican HS brain, muscle L02896 (rat)
K-glypican HS brain, kidney X83577 (mouse)
Cerebroglycan HS brain L20468 (rat)

PG, proteoglycan; GAG, glycosaminoglycan; CS, chondroitin sulfate;
KS, keratan sulfate; DS, dermatan sulfate; HS, heparan sulfate.
* A portion is linked to the plasma membrane through GPI.
** A soluble splicing variant of RPTP zeta/beta is called "phosphacan".



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