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Literature Search on Glycoscience Research

Time conducted: October 29 - December 5, 2011glycoprotein  |  glycolipid  |  proteoglycan  |  glycosaminoglycan  |  5b. Cancer related terms ↓
Note : "single term search (total)" means the total of papers obtained by the search term (single search).

5a-1. glycoprotein

From  1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 0 0  
To  1954 1959 1964 1969 1974 1979 1984 1989 1994 1999 2004 2009 2010 3000 3000  
glycoprotein 36 353 737 1,630 3,315 7,001 11,204 19,436 29,429 38,567 48,078 38,608 8,087 209,464    
                                Single term
search (total)
 
1 acidosis 0 0 0 1 3 5 4 11 5 10 19 43 11 116 35,098 0.33%
2 AIDS 0 0 0 0 1 4 17 242 441 590 681 467 91 2,585 182,623 1.42%
3 allergy 0 1 4 2 4 3 10 74 236 511 625 462 113 2,089 92,148 2.27%
4 Alzheimer's disease 0 0 0 0 0 0 2 29 107 146 258 210 75 853 78,861 1.08%
5 amyotrophic lateral sclerosis (ALS) 0 0 0 0 0 3 1 6 15 15 24 42 12 122 13,838 0.88%
6 anemia 0 1 0 7 12 32 48 81 140 154 198 199 38 929 139,892 0.66%
7 angina, (angina pectoris)  0 0 1 1 0 0 2 15 30 247 508 264 42 1,124 56,825 1.98%
8 apoplexy 0 0 0 0 0 0 0 0 1 0 2 0 0 3 2,323 0.13%
9 arteriosclerosis 0 4 23 27 29 28 33 60 105 194 353 70 4 931 68,593 1.36%
10 arthritis 1 14 24 15 22 49 62 112 225 327 640 489 88 2,983 156,446 1.91%
11 articular rheumatism 1 2 1 1 0 0 0 0 0 0 0 0 0 5 505 0.99%
12 articular rheumatism OR rheumatoid arthritis 2 14 18 10 18 37 52 87 143 238 441 338 58 1,459 95,448 1.53%
13 asthma 0 0 4 10 13 12 9 39 122 373 351 213 52 1,216 123,051 0.99%
14 atherosclerosis 0 0 7 10 11 17 16 51 140 285 536 453 109 1,679 83,845 2.00%
15 atopic dermatitis 0 0 2 0 1 2 0 0 18 79 93 39 12 253 15,955 1.59%
16 autoimmune disorder 0 0 2 3 9 16 35 78 161 392 545 428 78 1,765 54,548 3.24%
17 cancer 1 4 13 15 26 170 338 1,276 2,869 3,946 5,606 5,402 1,238 21,420 1,065,654 2.01%
18 cardiomyopathy  0 0 0 1 1 5 3 6 11 64 140 90 20 348 58,948 0.59%
19 cataract 0 0 4 1 3 5 5 24 21 35 46 26 3 177 47,295 0.37%
20 CDG, congenital disorders of glycosylation 0 0 0 0 0 0 0 0 0 124 81 58 4 275 535 51.40%
21 cerebral hemorrhage 0 0 0 0 1 0 1 5 4 10 33 26 3 85 27,169 0.31%
22 cerebral infarction 0 0 0 0 0 1 1 13 11 23 36 32 4 125 21,943 0.57%
23 cerebral palsy 0 0 0 0 0 0 0 0 0 0 4 3 0 7 17,180 0.04%
24 cholera 0 0 0 0 4 27 30 50 104 91 88 58 20 475 22,245 2.14%
25 cirrhosis 0 1 9 6 37 36 49 67 116 137 162 190 55 878 86,528 1.01%
26 communicable disease 0 0 1 0 0 0 0 3 13 16 19 28 6 88 38,073 0.23%
27 connective tissue disease 0 0 0 0 1 1 9 10 19 30 21 15 4 110 9,252 1.19%
28 Creutzfeldt-Jakob disease (CJD) 0 0 0 0 0 0 1 10 10 10 41 12 1 86 6,422 1.34%
29 Crohn's disease 0 0 1 0 3 7 15 30 34 47 111 106 11 369 34,089 1.08%
30 cystitis 0 0 0 1 1 2 1 2 7 12 8 22 9 67 10,079 0.66%
31 depressive disorder 0 0 0 0 0 0 1 4 10 51 125 46 7 243 69,928 0.35%
32 dermatitis 0 0 3 0 4 5 5 11 45 134 162 90 21 489 64,692 0.76%
33 diabetes 0 13 18 21 38 64 122 250 326 474 800 785 189 3,159 368,836 0.86%
34 diabetic nephropathy 0 1 0 4 8 13 9 18 27 26 46 34 19 207 20,367 1.02%
35 diphtheria 0 0 0 2 0 4 9 11 20 34 25 19 5 129 16,458 0.78%
36 disc herniation 0 0 0 0 0 0 0 0 0 0 3 2 1 6 3,287 0.18%
37 emphysema 0 1 1 5 9 7 9 10 6 11 21 24 5 108 26,001 0.42%
38 epidemic disease 0 0 0 0 0 0 0 0 2 0 1 0 0 2 392 0.51%
39 Fabry disease 0 0 0 0 1 1 3 2 2 2 8 9 2 31 2,481 1.25%
40 Gaucher's disease 0 0 0 1 5 9 9 17 20 20 14 9 5 110 4,115 2.67%
41 genetic disease 0 0 0 0 0 1 0 3 9 14 15 17 0 60 4,093 1.47%
42 Guillain-Barre syndrome 0 0 0 0 0 0 1 8 6 11 19 16 6 70 6,070 1.15%
43 heart failure 0 1 0 1 3 2 6 7 9 49 169 145 36 446 117,868 0.38%
44 hepatitis 0 2 13 14 36 44 81 114 228 524 733 652 144 2,652 172,228 1.54%
45 hereditary disease 0 0 0 0 0 0 1 1 1 1 4 4 0 14 1,393 1.01%
46 hereditary disorder 0 0 0 0 0 1 1 4 1 6 5 1 0 20 856 2.34%
47 herpes 0 0 1 0 21 48 205 462 571 536 590 528 112 3,130 54,343 5.76%
48 high blood pressure 0 0 0 0 0 1 0 1 0 1 1 3 0 8 9,240 0.09%
49 HIV 0 0 0 0 0 0 4 345 1,185 1,525 1,776 1,551 347 6,966 239,796 2.90%
50 hyperlipemia 0 0 1 2 2 4 5 7 12 28 58 28 7 152 22,806 0.67%
51 hypertension 0 0 3 11 4 14 25 44 55 129 286 357 77 1,035 337,601 0.31%
52 IgA nephropathy 0 0 0 0 0 1 2 7 18 22 18 21 3 93 5,524 1.68%
53 infection 0 2 5 14 36 148 390 980 1,863 2,784 4,137 3,827 842 15,461 740,014 2.09%
54 inflammation 1 5 12 34 43 42 97 287 528 929 2,197 2,074 487 6,888 247,276 2.79%
55 influenza 0 1 8 12 44 94 172 381 526 721 759 1,083 383 4,373 64,825 6.75%
56 inherited metabolic disorder (IMD) 0 0 0 0 0 1 0 0 3 2 2 1 0 9 223 4.04%
57 insomnia 0 0 0 0 0 0 0 0 0 3 9 3 1 15 9,945 0.15%
58 interstitial pneumonia 0 0 0 1 0 0 0 1 3 24 37 14 3 85 4,420 1.92%
59 leukemia 0 3 11 10 76 349 591 811 1,275 1,666 1,645 1,145 205 7,851 239,198 3.28%
60 life style disease 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0.00%
61 lung fibrosis 0 0 1 2 1 1 8 13 21 47 61 46 14 215 19,423 1.11%
62 lymphoma 0 1 4 5 22 63 192 293 485 661 637 466 73 2,940 159,500 1.84%
63 lysosomal disease 0 0 0 0 0 6 2 6 13 14 14 18 2 75 984 7.62%
64 malaria 0 0 0 2 5 6 27 66 82 68 96 109 18 488 60,267 0.81%
65 malignancy 0 0 0 0 4 23 46 98 151 155 271 223 53 1,057 78,464 1.35%
66 metastasis 0 0 1 3 14 52 108 223 426 642 1,043 953 204 3,772 201,531 1.87%
67 mucopolysaccharidosis, MPS 0 0 1 4 11 20 15 4 7 5 7 29 2 107 5,450 1.96%
68 multiple sclerosis (MS)  0 0 5 7 2 7 24 35 62 171 398 502 127 1,395 47,884 2.91%
69 muscular dystrophy 0 3 2 0 0 7 12 17 76 264 300 146 25 868 21,591 4.02%
70 myocardial infarction 0 2 10 9 13 17 36 69 94 406 1,207 901 194 3,049 169,655 1.80%
71 neurological disorder 0 0 0 0 0 1 1 3 1 4 9 8 0 28 2,401 1.17%
72 neuromuscular disease 0 0 0 0 0 2 2 9 12 26 36 21 1 113 11,134 1.01%
73 osteoarthritis 0 0 0 1 4 10 10 19 49 83 160 158 45 546 45,531 1.20%
74 osteoporosis 0 0 0 0 0 0 2 1 16 36 263 165 11 490 54,275 0.90%
75 pancreatitis 0 0 0 0 3 7 9 26 44 35 66 81 17 292 49,738 0.59%
76 parasitic disease 0 0 0 0 0 0 1 8 18 18 40 27 8 125 15,868 0.79%
77 Parkinson's disease 0 0 0 0 0 0 0 3 29 130 336 115 13 627 58,845 1.07%
78 pollinosis (hay fever, HF) 0 0 1 0 0 0 1 4 6 12 16 5 0 45 4,476 1.01%
79 rheumatoid arthritis 1 13 17 9 18 37 52 87 143 238 441 338 58 1,455 95,055 1.53%
80 schizophrenia 0 0 3 1 2 6 9 5 14 65 118 78 21 336 95,499 0.35%
81 spinal cord injury 0 0 0 0 0 0 1 3 11 15 56 86 21 197 29,404 0.67%
82 subarachnoid hemorrhage 0 0 0 1 0 0 0 4 1 3 10 15 3 39 19,472 0.20%
83 thrombosis 0 0 1 0 4 8 48 284 457 821 1,172 1,112 243 4,243 135,988 3.12%
84 tuberculosis, TB 1 19 23 24 8 7 10 27 52 88 181 108 27 588 190,844 0.31%
85 tumor 1 1 9 21 71 409 801 2,551 4,945 7,122 10,566 8,169 1,590 36,703 1,069,803 3.43%
86 vaccine 0 0 1 5 7 40 106 455 926 1,379 1,918 2,255 566 8,007 198,178 4.04%
87 viral disease 0 0 1 0 5 9 23 31 81 96 140 110 24 530 34,751 1.53%
88 virus 0 1 11 35 306 1,036 1,700 2,907 4,575 5,331 6,318 6,324 1,481 30,850 582,926 5.29%
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5a-2. glycolipid

From  1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 0 0  
To  1954 1959 1964 1969 1974 1979 1984 1989 1994 1999 2004 2009 2010 3000 3000  
glycolipid 3 11 78 465 1,040 1,118 1,334 1,957 2,111 1,724 2,006 2,277 602 14,953    
                                Single term
search (total)
 
1 acidosis 0 0 0 2 0 1 0 1 1 0 0 0 1 6 35,098 0.02%
2 AIDS 0 0 0 0 0 0 2 5 13 20 15 18 6 79 182,623 0.04%
3 allergy 0 0 0 0 2 0 1 5 3 15 39 49 12 129 92,148 0.14%
4 Alzheimer's disease 0 0 0 2 0 0 1 3 1 7 3 8 1 27 78,861 0.03%
5 amyotrophic lateral sclerosis (ALS) 0 0 0 0 0 0 2 1 4 5 1 0 0 13 13,838 0.09%
6 anemia 0 0 0 1 4 1 1 9 7 10 5 1 3 42 139,892 0.03%
7 angina, (angina pectoris)  0 0 0 0 0 0 0 0 1 0 2 0 0 3 56,825 0.01%
8 apoplexy 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2,323 0.00%
9 arteriosclerosis 0 0 0 4 0 2 2 1 2 2 6 3 1 24 68,593 0.03%
10 arthritis 0 0 0 13 6 1 2 3 7 11 5 20 5 75 156,446 0.05%
11 articular rheumatism 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505 0.00%
12 articular rheumatism OR rheumatoid arthritis 0 0 0 1 2 0 2 2 4 6 4 13 4 40 95,448 0.04%
13 asthma 0 0 0 0 0 2 0 5 0 3 1 13 3 30 123,051 0.02%
14 atherosclerosis 0 0 0 0 0 0 2 1 1 2 8 19 1 37 83,845 0.04%
15 atopic dermatitis 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15,955 0.00%
16 autoimmune disorder 0 0 0 0 2 1 11 14 20 24 40 50 6 175 54,548 0.32%
17 cancer 0 0 0 3 6 8 53 136 141 117 136 187 45 851 1,065,654 0.08%
18 cardiomyopathy  0 0 0 0 0 1 0 3 7 0 2 5 0 19 58,948 0.03%
19 cataract 0 0 0 1 3 2 2 1 3 2 2 0 0 16 47,295 0.03%
20 CDG, congenital disorders of glycosylation 0 0 0 0 0 0 0 0 0 2 1 2 0 5 535 0.93%
21 cerebral hemorrhage 0 0 0 0 0 1 0 0 0 0 0 0 0 1 27,169 0.00%
22 cerebral infarction 0 0 0 0 0 1 0 0 2 0 1 0 0 4 21,943 0.02%
23 cerebral palsy 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17,180 0.00%
24 cholera 0 0 0 0 5 16 13 16 21 24 22 16 3 140 22,245 0.63%
25 cirrhosis 0 0 0 0 3 0 0 6 4 1 2 3 0 20 86,528 0.02%
26 communicable disease 0 0 0 0 0 0 0 0 1 2 1 2 0 6 38,073 0.02%
27 connective tissue disease 0 0 0 0 0 0 1 0 0 0 0 0 0 1 9,252 0.01%
28 Creutzfeldt-Jakob disease (CJD) 0 0 0 0 0 0 1 2 2 1 1 0 0 7 6,422 0.11%
29 Crohn's disease 0 0 0 0 0 0 0 3 5 2 3 2 0 14 34,089 0.04%
30 cystitis 0 0 0 0 0 0 2 1 1 0 1 0 0 5 10,079 0.05%
31 depressive disorder 0 0 0 0 0 0 0 0 0 0 2 0 0 2 69,928 0.00%
32 dermatitis 0 0 0 0 1 1 0 1 1 1 4 4 1 14 64,692 0.02%
33 diabetes 0 0 0 4 0 2 6 23 19 22 28 27 7 142 368,836 0.04%
34 diabetic nephropathy 0 0 0 0 0 0 0 0 1 0 2 1 1 5 20,367 0.02%
35 diphtheria 0 0 0 0 3 1 1 1 0 1 2 1 0 11 16,458 0.07%
36 disc herniation 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3,287 0.00%
37 emphysema 0 0 0 0 1 0 0 1 0 0 1 1 0 4 26,001 0.02%
38 epidemic disease 0 0 0 0 0 0 0 0 0 0 0 1 0 1 392 0.26%
39 Fabry disease 0 0 0 0 28 18 18 10 13 11 25 40 10 174 2,481 7.01%
40 Gaucher's disease 0 0 0 17 40 13 10 7 14 20 34 10 4 171 4,115 4.16%
41 genetic disease 0 0 0 0 0 0 0 1 0 1 1 0 1 5 4,093 0.12%
42 Guillain-Barre syndrome 0 0 0 0 0 0 0 4 17 28 19 17 5 95 6,070 1.57%
43 heart failure 0 0 0 1 0 0 1 2 2 0 1 1 0 8 117,868 0.01%
44 hepatitis 0 0 0 0 2 5 0 6 4 3 10 17 3 52 172,228 0.03%
45 hereditary disease 0 0 0 0 0 2 0 0 1 1 0 0 1 5 1,393 0.36%
46 hereditary disorder 0 0 0 0 0 0 0 0 0 1 0 0 0 1 856 0.12%
47 herpes 0 0 0 0 2 3 2 4 4 2 4 2 0 24 54,343 0.04%
48 high blood pressure 0 0 0 0 0 0 0 1 0 0 0 0 0 1 9,240 0.01%
49 HIV 0 0 0 0 0 0 0 2 24 45 47 33 9 166 239,796 0.07%
50 hyperlipemia 0 0 0 0 4 3 0 1 1 0 2 3 1 16 22,806 0.07%
51 hypertension 0 0 0 1 1 0 2 5 0 2 2 2 0 15 337,601 0.00%
52 IgA nephropathy 0 0 0 0 0 0 0 0 2 1 0 1 0 4 5,524 0.07%
53 infection 0 1 0 3 5 22 39 102 135 130 195 190 44 886 740,014 0.12%
54 inflammation 0 0 0 0 1 3 9 16 27 22 58 70 22 242 247,276 0.10%
55 influenza 0 0 0 2 1 4 8 10 13 15 18 17 6 95 64,825 0.15%
56 inherited metabolic disorder (IMD) 0 0 0 0 0 0 0 0 0 1 0 2 0 3 223 1.35%
57 insomnia 0 0 0 0 0 0 0 0 0 0 1 0 0 1 9,945 0.01%
58 interstitial pneumonia 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4,420 0.00%
59 leukemia 0 0 0 0 14 8 48 43 27 17 15 18 1 195 239,198 0.08%
60 life style disease 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0.00%
61 lung fibrosis 0 0 0 0 0 0 2 3 0 0 1 0 0 6 19,423 0.03%
62 lymphoma 0 0 0 1 4 3 30 40 45 22 14 8 2 170 159,500 0.11%
63 lysosomal disease 0 0 0 0 0 1 2 2 3 4 10 6 1 30 984 3.05%
64 malaria 0 0 0 0 1 2 1 2 11 5 8 13 6 46 60,267 0.08%
65 malignancy 0 0 0 0 0 6 4 12 7 4 10 9 0 54 78,464 0.07%
66 metastasis 0 0 0 0 5 3 14 30 19 22 36 27 7 168 201,531 0.08%
67 mucopolysaccharidosis, MPS 0 0 1 16 21 8 2 1 2 4 6 0 0 62 5,450 1.14%
68 multiple sclerosis (MS)  0 0 0 1 1 1 10 7 7 5 17 7 4 71 47,884 0.15%
69 muscular dystrophy 0 0 0 0 0 0 7 0 1 3 1 1 0 13 21,591 0.06%
70 myocardial infarction 0 0 0 0 2 1 0 1 3 1 5 3 0 16 169,655 0.01%
71 neurological disorder 0 0 0 0 0 0 2 0 1 3 1 2 2 10 2,401 0.42%
72 neuromuscular disease 0 0 0 0 2 0 1 2 5 2 2 0 0 14 11,134 0.13%
73 osteoarthritis 0 0 0 0 0 0 0 0 1 2 1 2 1 8 45,531 0.02%
74 osteoporosis 0 0 0 0 0 0 0 0 0 0 1 1 0 3 54,275 0.01%
75 pancreatitis 0 0 0 0 0 0 0 5 0 0 0 1 0 6 49,738 0.01%
76 parasitic disease 0 0 0 0 0 0 0 4 1 2 3 1 2 13 15,868 0.08%
77 Parkinson's disease 0 0 0 2 0 0 0 0 0 2 2 1 1 9 58,845 0.02%
78 pollinosis (hay fever, HF) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4,476 0.00%
79 rheumatoid arthritis 0 0 0 1 2 0 2 2 4 6 4 13 4 40 95,055 0.04%
80 schizophrenia 0 0 0 1 0 0 0 1 0 0 0 1 1 4 95,499 0.00%
81 spinal cord injury 0 0 0 0 0 0 0 0 2 1 0 0 0 4 29,404 0.01%
82 subarachnoid hemorrhage 0 0 0 0 0 1 0 0 0 0 0 0 0 1 19,472 0.01%
83 thrombosis 0 0 0 0 1 0 1 1 8 7 6 4 1 29 135,988 0.02%
84 tuberculosis, TB 0 3 4 38 49 21 22 61 75 73 86 134 17 602 190,844 0.32%
85 tumor 0 0 1 4 18 43 82 258 289 240 256 267 53 1,533 1,069,803 0.14%
86 vaccine 0 1 0 4 10 29 20 33 29 45 61 110 33 383 198,178 0.19%
87 viral disease 0 0 0 0 2 0 0 3 1 2 2 7 1 19 34,751 0.05%
88 virus 0 0 0 7 57 55 50 81 72 69 86 85 17 589 582,926 0.10%
pagetop


5a-3. proteoglycan

From  1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 0 0  
To  1954 1959 1964 1969 1974 1979 1984 1989 1994 1999 2004 2009 2010 3000 3000  
proteoglycan 0 0 0 5 159 841 1,656 2,855 4,200 4,719 5,864 6,214 1,264 28,342    
                                Single term
search (total)
 
1 acidosis 0 0 0 0 0 0 0 0 3 3 2 0 1 10 35,098 0.03%
2 AIDS 0 0 0 0 0 0 2 2 6 15 21 21 2 70 182,623 0.04%
3 allergy 0 0 0 0 0 0 0 4 11 13 12 20 5 66 92,148 0.07%
4 Alzheimer's disease 0 0 0 0 0 0 0 14 51 82 63 46 12 274 78,861 0.35%
5 amyotrophic lateral sclerosis (ALS) 0 0 0 0 0 0 0 0 2 2 2 3 0 10 13,838 0.07%
6 anemia 0 0 0 0 0 0 0 0 2 5 2 7 0 16 139,892 0.01%
7 angina, (angina pectoris)  0 0 0 0 0 0 0 1 1 0 5 6 1 15 56,825 0.03%
8 apoplexy 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2,323 0.00%
9 arteriosclerosis 0 0 0 0 6 11 18 48 62 74 110 22 1 351 68,593 0.51%
10 arthritis 0 0 0 0 4 54 80 153 209 204 239 253 39 1,256 156,446 0.80%
11 articular rheumatism 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505 0.00%
12 articular rheumatism OR rheumatoid arthritis 0 0 0 0 4 37 44 82 101 88 109 107 15 600 95,448 0.63%
13 asthma 0 0 0 0 0 0 5 5 4 14 23 33 6 96 123,051 0.08%
14 atherosclerosis 0 0 0 0 0 7 12 42 50 108 147 157 34 568 83,845 0.68%
15 atopic dermatitis 0 0 0 0 0 0 0 0 0 1 3 2 0 6 15,955 0.04%
16 autoimmune disorder 0 0 0 0 0 3 3 10 8 14 20 24 3 85 54,548 0.16%
17 cancer 0 0 0 0 0 4 42 124 237 367 678 802 185 2,506 1,065,654 0.24%
18 cardiomyopathy  0 0 0 0 0 0 0 0 2 3 6 9 0 21 58,948 0.04%
19 cataract 0 0 0 0 0 1 3 3 6 7 10 10 1 41 47,295 0.09%
20 CDG, congenital disorders of glycosylation 0 0 0 0 0 0 0 0 0 3 0 0 1 4 535 0.75%
21 cerebral hemorrhage 0 0 0 0 0 0 1 0 0 1 2 2 1 6 27,169 0.02%
22 cerebral infarction 0 0 0 0 0 0 0 0 0 0 2 3 1 5 21,943 0.02%
23 cerebral palsy 0 0 0 0 0 0 1 0 0 0 3 1 0 5 17,180 0.03%
24 cholera 0 0 0 0 0 0 0 7 6 3 12 5 2 34 22,245 0.15%
25 cirrhosis 0 0 0 0 1 0 6 7 24 13 17 22 8 100 86,528 0.12%
26 communicable disease 0 0 0 0 0 0 0 0 0 0 0 0 1 1 38,073 0.00%
27 connective tissue disease 0 0 0 0 0 1 10 6 9 3 5 11 0 48 9,252 0.52%
28 Creutzfeldt-Jakob disease (CJD) 0 0 0 0 0 0 0 1 1 1 1 0 0 6 6,422 0.09%
29 Crohn's disease 0 0 0 0 0 0 0 0 0 2 2 7 0 11 34,089 0.03%
30 cystitis 0 0 0 0 0 0 0 1 4 3 2 3 0 13 10,079 0.13%
31 depressive disorder 0 0 0 0 0 0 0 0 0 0 1 1 0 2 69,928 0.00%
32 dermatitis 0 0 0 0 0 0 3 0 2 5 5 3 1 19 64,692 0.03%
33 diabetes 0 0 0 0 0 4 18 31 67 67 70 111 27 405 368,836 0.11%
34 diabetic nephropathy 0 0 0 0 0 0 2 9 30 32 27 30 5 140 20,367 0.69%
35 diphtheria 0 0 0 0 0 0 1 0 0 3 3 1 0 8 16,458 0.05%
36 disc herniation 0 0 0 0 0 0 2 2 1 3 9 10 0 28 3,287 0.85%
37 emphysema 0 0 0 0 0 5 3 6 3 4 2 10 1 34 26,001 0.13%
38 epidemic disease 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392 0.00%
39 Fabry disease 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2,481 0.00%
40 Gaucher's disease 0 0 0 0 0 0 0 0 0 1 0 0 0 1 4,115 0.02%
41 genetic disease 0 0 0 0 0 0 0 1 1 2 5 4 0 14 4,093 0.34%
42 Guillain-Barre syndrome 0 0 0 0 0 0 0 0 0 2 0 0 1 3 6,070 0.05%
43 heart failure 0 0 0 0 0 0 0 1 0 7 7 14 0 31 117,868 0.03%
44 hepatitis 0 0 0 0 1 0 3 0 2 4 14 17 5 48 172,228 0.03%
45 hereditary disease 0 0 0 0 0 0 0 1 0 1 1 1 1 5 1,393 0.36%
46 hereditary disorder 0 0 0 0 0 0 0 0 0 0 0 3 0 4 856 0.47%
47 herpes 0 0 0 0 0 1 3 1 12 17 16 22 7 79 54,343 0.15%
48 high blood pressure 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9,240 0.00%
49 HIV 0 0 0 0 0 0 0 3 4 22 56 61 6 152 239,796 0.06%
50 hyperlipemia 0 0 0 0 0 0 0 3 1 7 5 9 1 26 22,806 0.11%
51 hypertension 0 0 0 0 1 2 8 8 10 15 25 35 8 116 337,601 0.03%
52 IgA nephropathy 0 0 0 0 0 0 0 1 8 3 3 1 1 18 5,524 0.33%
53 infection 0 0 0 0 0 5 22 24 36 99 160 176 36 571 740,014 0.08%
54 inflammation 0 0 0 0 1 17 37 70 128 171 303 386 71 1,228 247,276 0.50%
55 influenza 0 0 0 0 0 1 0 2 1 0 2 2 0 8 64,825 0.01%
56 inherited metabolic disorder (IMD) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223 0.00%
57 insomnia 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9,945 0.00%
58 interstitial pneumonia 0 0 0 0 0 0 0 0 0 1 1 1 0 3 4,420 0.07%
59 leukemia 0 0 0 0 0 1 6 23 46 69 53 63 11 278 239,198 0.12%
60 life style disease 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0.00%
61 lung fibrosis 0 0 0 0 0 2 4 5 8 13 13 9 4 60 19,423 0.31%
62 lymphoma 0 0 0 0 0 0 3 13 21 40 43 35 2 161 159,500 0.10%
63 lysosomal disease 0 0 0 0 0 0 0 0 2 0 1 3 0 7 984 0.71%
64 malaria 0 0 0 0 0 0 0 0 4 13 20 21 6 66 60,267 0.11%
65 malignancy 0 0 0 0 0 1 7 7 13 22 34 36 7 130 78,464 0.17%
66 metastasis 0 0 0 0 0 1 27 58 78 138 260 268 63 912 201,531 0.45%
67 mucopolysaccharidosis, MPS 0 0 0 1 2 5 8 4 12 7 5 10 2 58 5,450 1.06%
68 multiple sclerosis (MS)  0 0 0 0 0 0 1 1 2 5 23 31 11 79 47,884 0.16%
69 muscular dystrophy 0 0 0 0 0 0 0 3 3 8 17 22 2 56 21,591 0.26%
70 myocardial infarction 0 0 0 0 0 2 0 1 4 6 30 32 7 85 169,655 0.05%
71 neurological disorder 0 0 0 0 0 0 0 0 0 0 1 0 0 1 2,401 0.04%
72 neuromuscular disease 0 0 0 0 0 0 0 2 0 1 3 9 1 17 11,134 0.15%
73 osteoarthritis 0 0 0 0 12 44 68 150 212 213 337 402 95 1,581 45,531 3.47%
74 osteoporosis 0 0 0 0 0 2 3 7 8 9 16 16 2 68 54,275 0.13%
75 pancreatitis 0 0 0 0 0 0 0 0 1 3 8 8 1 23 49,738 0.05%
76 parasitic disease 0 0 0 0 0 0 0 0 0 1 1 3 1 6 15,868 0.04%
77 Parkinson's disease 0 0 0 0 0 0 0 0 1 3 1 12 4 22 58,845 0.04%
78 pollinosis (hay fever, HF) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4,476 0.00%
79 rheumatoid arthritis 0 0 0 0 4 37 44 82 101 88 109 107 15 600 95,055 0.63%
80 schizophrenia 0 0 0 0 0 0 0 0 0 0 4 5 4 16 95,499 0.02%
81 spinal cord injury 0 0 0 0 0 0 0 0 2 6 54 119 34 245 29,404 0.83%
82 subarachnoid hemorrhage 0 0 0 0 0 0 0 0 0 0 0 1 0 1 19,472 0.01%
83 thrombosis 0 0 0 0 0 0 3 11 14 25 24 25 8 115 135,988 0.08%
84 tuberculosis, TB 0 0 0 0 0 0 1 5 5 5 5 4 1 27 190,844 0.01%
85 tumor 0 0 0 0 0 15 101 309 491 814 1,225 1,309 253 4,598 1,069,803 0.43%
86 vaccine 0 0 0 0 0 0 8 12 8 12 20 22 8 96 198,178 0.05%
87 viral disease 0 0 0 0 0 0 1 3 0 7 1 3 1 16 34,751 0.05%
88 virus 0 0 0 0 0 15 21 30 41 100 170 190 38 621 582,926 0.11%
pagetop


5a-4. glycosaminoglycan

From  1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 0 0  
To  1954 1959 1964 1969 1974 1979 1984 1989 1994 1999 2004 2009 2010 3000 3000  
glycosaminoglycan 0 258 1,037 2,495 3,368 2,497 2,524 2,918 2,953 2,782 2,966 3,530 971 28,782    
                                Single term
search (total)
 
1 acidosis 0 0 1 1 0 2 1 0 0 2 1 2 0 13 35,098 0.04%
2 AIDS 0 0 0 0 0 2 1 2 6 7 7 10 1 37 182,623 0.02%
3 allergy 0 1 7 5 1 1 0 3 11 8 13 15 4 69 92,148 0.07%
4 Alzheimer's disease 0 0 0 0 0 0 0 19 23 54 35 25 11 172 78,861 0.22%
5 amyotrophic lateral sclerosis (ALS) 0 0 0 1 1 0 0 1 3 3 1 1 0 11 13,838 0.08%
6 anemia 0 0 3 4 11 2 7 1 3 5 1 7 1 45 139,892 0.03%
7 angina, (angina pectoris)  0 0 0 4 1 1 0 2 1 0 3 2 0 15 56,825 0.03%
8 apoplexy 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2,323 0.00%
9 arteriosclerosis 0 5 57 142 142 75 49 71 48 35 47 8 1 679 68,593 0.99%
10 arthritis 0 3 13 39 50 53 55 75 81 63 76 114 24 660 156,446 0.42%
11 articular rheumatism 0 0 0 0 0 0 0 0 1 0 0 0 0 1 505 0.20%
12 articular rheumatism OR rheumatoid arthritis 0 3 7 26 36 37 32 38 48 31 35 34 6 339 95,448 0.36%
13 asthma 0 0 4 9 10 3 2 1 2 8 10 11 1 66 123,051 0.05%
14 atherosclerosis 0 4 15 33 68 53 44 64 56 50 66 60 23 535 83,845 0.64%
15 atopic dermatitis 0 0 1 0 1 0 1 0 1 3 1 0 0 8 15,955 0.05%
16 autoimmune disorder 0 0 3 4 6 2 4 4 5 15 12 10 1 68 54,548 0.12%
17 cancer 0 2 5 14 27 35 25 66 103 100 114 168 39 716 1,065,654 0.07%
18 cardiomyopathy  0 0 0 6 4 2 0 0 2 2 6 10 0 35 58,948 0.06%
19 cataract 0 0 0 2 2 5 2 2 3 9 7 6 0 40 47,295 0.08%
20 CDG, congenital disorders of glycosylation 0 0 0 0 0 0 0 0 0 0 1 0 0 1 535 0.19%
21 cerebral hemorrhage 0 0 1 0 0 0 1 0 0 0 1 1 1 8 27,169 0.03%
22 cerebral infarction 0 0 0 0 0 0 0 2 1 0 0 0 0 4 21,943 0.02%
23 cerebral palsy 0 0 0 0 1 0 0 0 0 0 0 0 0 2 17,180 0.01%
24 cholera 0 0 0 0 2 1 1 4 1 3 2 2 1 16 22,245 0.07%
25 cirrhosis 0 3 9 19 21 7 15 12 19 6 9 3 1 124 86,528 0.14%
26 communicable disease 0 0 0 0 0 0 0 0 0 1 0 3 2 6 38,073 0.02%
27 connective tissue disease 0 0 1 0 4 4 10 12 5 1 3 5 1 47 9,252 0.51%
28 Creutzfeldt-Jakob disease (CJD) 0 0 0 0 0 1 1 1 4 1 3 4 0 16 6,422 0.25%
29 Crohn's disease 0 0 0 2 1 0 0 1 2 1 4 4 0 15 34,089 0.04%
30 cystitis 0 0 0 0 0 0 2 9 17 16 17 34 2 105 10,079 1.04%
31 depressive disorder 0 0 0 0 0 0 0 1 0 0 2 0 0 3 69,928 0.00%
32 dermatitis 0 0 2 4 8 2 2 3 5 10 7 2 0 45 64,692 0.07%
33 diabetes 0 2 12 32 53 17 46 44 49 68 55 64 23 472 368,836 0.13%
34 diabetic nephropathy 0 0 2 0 8 1 2 11 13 38 17 25 7 128 20,367 0.63%
35 diphtheria 0 0 0 1 0 0 0 0 0 0 0 0 0 1 16,458 0.01%
36 disc herniation 0 0 0 0 0 0 0 0 0 0 1 2 0 4 3,287 0.12%
37 emphysema 0 0 0 4 10 5 6 8 3 4 2 0 0 43 26,001 0.17%
38 epidemic disease 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392 0.00%
39 Fabry disease 0 0 0 0 2 0 1 0 0 0 0 2 0 6 2,481 0.24%
40 Gaucher's disease 0 0 0 9 15 2 0 0 0 0 1 3 0 30 4,115 0.73%
41 genetic disease 0 0 0 0 0 1 1 2 3 1 0 3 0 11 4,093 0.27%
42 Guillain-Barre syndrome 0 0 0 0 0 0 0 1 0 1 0 0 0 2 6,070 0.03%
43 heart failure 0 0 0 0 4 0 0 1 3 2 4 9 1 27 117,868 0.02%
44 hepatitis 0 0 10 7 13 7 5 2 5 4 18 18 3 94 172,228 0.05%
45 hereditary disease 0 0 0 0 0 0 0 0 1 0 1 0 1 3 1,393 0.22%
46 hereditary disorder 0 0 0 0 0 0 0 0 0 0 0 2 0 2 856 0.23%
47 herpes 0 0 1 0 1 2 1 1 13 11 15 15 2 67 54,343 0.12%
48 high blood pressure 0 0 0 0 0 0 1 0 0 0 0 0 0 1 9,240 0.01%
49 HIV 0 0 0 0 0 0 0 0 12 18 33 23 5 95 239,796 0.04%
50 hyperlipemia 0 0 3 12 13 13 10 6 2 3 3 2 0 67 22,806 0.29%
51 hypertension 0 0 12 17 24 15 17 15 19 20 22 32 7 208 337,601 0.06%
52 IgA nephropathy 0 0 0 0 0 0 0 0 3 4 0 2 0 10 5,524 0.18%
53 infection 0 0 1 7 4 14 20 37 46 75 141 116 31 511 740,014 0.07%
54 inflammation 0 2 22 32 40 19 31 70 84 105 151 228 65 879 247,276 0.36%
55 influenza 0 0 1 10 2 5 0 0 0 3 2 2 2 28 64,825 0.04%
56 inherited metabolic disorder (IMD) 0 0 0 0 0 1 0 0 1 0 0 0 0 3 223 1.35%
57 insomnia 0 0 0 0 0 0 0 0 0 1 2 0 0 3 9,945 0.03%
58 interstitial pneumonia 0 0 0 0 1 1 1 0 0 0 0 0 0 3 4,420 0.07%
59 leukemia 0 2 6 14 19 8 14 30 28 22 17 11 2 172 239,198 0.07%
60 life style disease 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0.00%
61 lung fibrosis 0 0 2 2 6 6 10 7 7 5 6 6 2 60 19,423 0.31%
62 lymphoma 0 0 4 2 6 2 3 10 9 9 8 6 1 60 159,500 0.04%
63 lysosomal disease 0 0 0 0 0 3 1 3 5 13 23 28 8 90 984 9.15%
64 malaria 0 0 0 0 1 0 0 0 3 14 21 9 1 53 60,267 0.09%
65 malignancy 0 0 0 0 1 5 8 5 10 6 12 8 3 60 78,464 0.08%
66 metastasis 0 0 3 8 11 12 14 28 29 25 41 68 9 255 201,531 0.13%
67 mucopolysaccharidosis, MPS 0 3 36 183 335 172 118 87 104 98 113 195 67 1,572 5,450 28.84%
68 multiple sclerosis (MS)  0 0 0 2 0 0 2 0 0 0 3 5 0 13 47,884 0.03%
69 muscular dystrophy 0 0 0 2 2 4 3 2 1 3 0 1 0 18 21,591 0.08%
70 myocardial infarction 0 0 2 21 8 6 10 8 8 4 3 10 9 89 169,655 0.05%
71 neurological disorder 0 0 0 0 0 0 0 0 1 0 0 0 0 1 2,401 0.04%
72 neuromuscular disease 0 0 0 1 0 0 0 1 0 1 1 1 0 5 11,134 0.04%
73 osteoarthritis 0 0 4 14 58 47 61 99 96 100 134 212 59 927 45,531 2.04%
74 osteoporosis 0 0 3 10 7 3 4 4 5 4 6 4 0 56 54,275 0.10%
75 pancreatitis 0 0 0 1 4 1 3 3 2 2 4 3 0 24 49,738 0.05%
76 parasitic disease 0 0 0 0 0 0 0 0 0 2 2 2 1 7 15,868 0.04%
77 Parkinson's disease 0 0 0 0 0 0 0 0 1 1 8 4 2 18 58,845 0.03%
78 pollinosis (hay fever, HF) 0 0 1 0 0 0 0 0 0 1 0 0 0 2 4,476 0.04%
79 rheumatoid arthritis 0 3 7 26 36 37 32 38 47 31 35 34 6 338 95,055 0.36%
80 schizophrenia 0 0 0 2 1 2 3 0 0 0 1 0 0 9 95,499 0.01%
81 spinal cord injury 0 0 0 0 0 2 2 0 3 0 4 15 7 40 29,404 0.14%
82 subarachnoid hemorrhage 0 0 0 0 0 0 0 1 0 0 0 1 0 2 19,472 0.01%
83 thrombosis 0 0 5 8 18 9 8 47 69 48 41 37 13 304 135,988 0.22%
84 tuberculosis, TB 0 2 10 17 17 9 2 5 5 3 7 5 1 83 190,844 0.04%
85 tumor 0 0 8 16 35 63 102 187 232 253 270 321 67 1,585 1,069,803 0.15%
86 vaccine 0 0 1 2 3 1 3 1 8 10 12 18 4 67 198,178 0.03%
87 viral disease 0 0 1 3 1 1 1 1 0 9 3 5 0 25 34,751 0.07%
88 virus 0 2 8 28 23 40 24 19 48 73 126 127 23 561 582,926 0.10%
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Time conducted: December 6, 2011glycoprotein  |  glycolipid  |  proteoglycan  |  glycosaminoglycan
Note : "single term search (total)" means the total of papers obtained by the search term (single search).

5b-1. glycoprotein

From  1970 1975 1980 1985 1990 1995 2000 2005 2010 0 0  
To  1974 1979 1984 1989 1994 1999 2004 2009 2010 3000 3000  
Pubmed overall 1,132,894 1,312,984 1,472,458 1,822,522 2,078,833 2,305,551 2,836,184 3,643,770 924,699 21,371,008    
glycoprotein 3,315 7,001 11,204 19,436 29,429 38,567 48,078 38,608 8,087 209,464   0.98%
cancer 26 170 338 1,276 2,869 3,946 5,606 5,402 1,238 21,420   10.23%
                        Single term
search (total)
 
1 bladder 0 0 4 11 41 43 57 54 20 235 17,828 1.32%
2 blood 0 0 0 1 0 0 0 2 0 3 482 0.62%
3 brain 0 0 0 0 0 0 5 19 4 30 1,157 2.59%
4 breast 1 25 56 135 285 466 649 884 223 2,839 142,904 1.99%
5 colon 0 2 12 49 91 136 212 197 55 773 24,488 3.16%
6 esophageal 0 0 3 5 5 11 14 19 7 67 9,541 0.70%
7 kidney 0 0 1 0 2 1 4 9 0 17 1,831 0.93%
8 liver 0 1 1 6 11 11 36 58 17 147 8,454 1.74%
9 lung 0 5 17 86 159 200 265 298 63 1,126 74,198 1.52%
10 ovarian 0 10 18 68 107 109 212 246 56 843 27,819 3.03%
11 pancreatic 0 2 9 24 43 47 83 126 22 380 16,215 2.34%
12 prostate 0 0 3 7 22 133 311 279 57 839 55,751 1.50%
13 rectum,rectal 0 0 1 0 2 5 4 8 5 27 11,795 0.23%
14 skin 0 0 0 1 0 10 17 17 6 52 9,855 0.53%
15 stomach, gastric 2 12 25 41 53 71 112 126 44 505 34,011 1.48%
16 testicular 0 2 2 4 3 5 5 6 0 27 4,024 0.67%
17 throat 0 0 0 0 0 0 0 0 0 0 43 0.00%
18 thyroid 0 1 1 3 2 10 22 24 3 68 10,433 0.65%
19 tongue 0 0 0 0 0 0 1 2 0 4 802 0.50%
20 uterine 0 2 1 1 0 0 3 2 0 11 2,041 0.54%
21 uterine cervical 0 0 3 0 2 2 2 5 2 15 815 1.84%
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5b-2. glycolipid

From  1970 1975 1980 1985 1990 1995 2000 2005 2010 0 0  
To  1974 1979 1984 1989 1994 1999 2004 2009 2010 3000 3000  
Pubmed overall 1,132,894 1,312,984 1,472,458 1,822,522 2,078,833 2,305,551 2,836,184 3,643,770 924,699 21,371,008    
glycolipid 1,040 1,118 1,334 1,957 2,111 1,724 2,006 2,277 602 14,953   0.07%
cancer 6 8 53 136 141 117 136 187 45 851   5.69%
                        Single term
search (total)
 
1 bladder 0 0 5 3 2 2 1 1 0 14 17,828 0.08%
2 blood 0 0 0 0 0 0 0 0 0 0 482 0.00%
3 brain 0 0 0 0 0 0 0 0 1 1 1,157 0.09%
4 breast 0 0 2 5 4 14 16 15 5 64 142,904 0.04%
5 colon 0 0 1 11 5 2 4 8 4 36 24,488 0.15%
6 esophageal 0 0 0 0 1 0 0 0 0 1 9,541 0.01%
7 kidney 0 0 0 0 0 0 0 0 0 0 1,831 0.00%
8 liver 0 0 0 4 0 0 1 1 0 7 8,454 0.08%
9 lung 0 0 4 23 6 5 2 3 2 48 74,198 0.06%
10 ovarian 0 0 0 8 6 4 6 4 0 29 27,819 0.10%
11 pancreatic 0 0 2 6 4 2 1 2 0 17 16,215 0.10%
12 prostate 0 0 0 1 2 1 5 5 2 15 55,751 0.03%
13 rectum,rectal 0 0 1 0 0 0 0 0 0 1 11,795 0.01%
14 skin 0 0 0 0 0 0 0 0 0 1 9,855 0.01%
15 stomach, gastric 0 0 6 12 18 4 2 2 0 44 34,011 0.13%
16 testicular 0 0 0 0 0 0 0 0 0 0 4,024 0.00%
17 throat 0 0 0 0 0 0 0 0 0 0 43 0.00%
18 thyroid 0 0 0 0 0 0 0 0 0 0 10,433 0.00%
19 tongue 0 0 0 0 0 0 0 0 0 0 802 0.00%
20 uterine 0 0 0 0 1 1 1 0 0 3 2,041 0.15%
21 uterine cervical 0 0 0 0 0 0 0 0 0 0 815 0.00%
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5b-3. proteoglycan

From  1970 1975 1980 1985 1990 1995 2000 2005 2010 0 0  
To  1974 1979 1984 1989 1994 1999 2004 2009 2010 3000 3000  
Pubmed overall 1,132,894 1,312,984 1,472,458 1,822,522 2,078,833 2,305,551 2,836,184 3,643,770 924,699 21,371,008    
proteoglycan 159 841 1,656 2,855 4,200 4,719 5,864 6,214 1,264 28,342   0.13%
cancer 0 4 42 124 237 367 678 802 185 2,506   8.84%
                        Single term
search (total)
 
1 bladder 0 0 2 2 5 3 5 6 2 25 17,828 0.14%
2 blood 0 0 0 0 0 0 0 0 0 0 482 0.00%
3 brain 0 0 0 0 0 0 1 0 0 1 1,157 0.09%
4 breast 0 0 1 10 23 48 83 122 28 322 142,904 0.23%
5 colon 0 0 2 3 12 20 28 26 2 98 24,488 0.40%
6 esophageal 0 0 0 3 0 4 3 5 1 16 9,541 0.17%
7 kidney 0 0 0 0 0 0 0 1 1 2 1,831 0.11%
8 liver 0 0 0 2 1 2 5 4 4 20 8,454 0.24%
9 lung 0 0 5 3 3 13 23 31 9 86 74,198 0.12%
10 ovarian 0 0 0 2 4 14 15 21 6 62 27,819 0.22%
11 pancreatic 0 0 0 1 3 5 35 27 4 78 16,215 0.48%
12 prostate 0 0 0 0 4 18 42 52 13 128 55,751 0.23%
13 rectum,rectal 0 0 1 3 1 0 0 3 1 9 11,795 0.08%
14 skin 0 0 0 0 1 0 0 3 0 6 9,855 0.06%
15 stomach, gastric 0 2 14 24 16 12 20 17 7 114 34,011 0.34%
16 testicular 0 0 0 0 0 0 0 2 0 2 4,024 0.05%
17 throat 0 0 0 0 0 0 0 0 0 0 43 0.00%
18 thyroid 0 0 0 0 0 0 0 3 0 3 10,433 0.03%
19 tongue 0 0 0 0 0 0 0 0 0 0 802 0.00%
20 uterine 0 0 0 0 0 0 0 1 0 1 2,041 0.05%
21 uterine cervical 0 0 0 1 0 0 1 0 0 2 815 0.25%
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5b-4. glycosaminoglycan

From  1970 1975 1980 1985 1990 1995 2000 2005 2010 0 0  
To  1974 1979 1984 1989 1994 1999 2004 2009 2010 3000 3000  
Pubmed overall 1,132,894 1,312,984 1,472,458 1,822,522 2,078,833 2,305,551 2,836,184 3,643,770 924,699 21,371,008    
glycosaminoglycan 3,368 2,497 2,524 2,918 2,953 2,782 2,966 3,530 971 28,782   0.13%
cancer 27 35 25 66 103 100 114 168 39 716   2.49%
                        Single term
search (total)
 
1 bladder 0 0 2 2 3 5 4 2 1 19 17,828 0.11%
2 blood 0 0 0 0 0 0 0 0 0 0 482 0.00%
3 brain 0 0 0 0 0 0 0 1 0 1 1,157 0.09%
4 breast 4 4 0 3 5 14 12 18 4 65 142,904 0.05%
5 colon 0 0 0 1 4 2 2 7 2 18 24,488 0.07%
6 esophageal 0 0 0 0 0 0 0 0 0 0 9,541 0.00%
7 kidney 0 0 0 0 0 0 0 0 0 0 1,831 0.00%
8 liver 0 0 0 0 0 0 0 0 0 0 8,454 0.00%
9 lung 0 1 3 4 4 1 3 1 2 19 74,198 0.03%
10 ovarian 0 0 0 0 2 2 3 2 0 10 27,819 0.04%
11 pancreatic 0 0 0 3 0 1 0 2 0 8 16,215 0.05%
12 prostate 0 0 0 0 2 7 5 5 2 21 55,751 0.04%
13 rectum,rectal 0 0 0 0 0 0 0 0 0 0 11,795 0.00%
14 skin 0 0 0 1 1 0 0 1 0 4 9,855 0.04%
15 stomach, gastric 1 4 5 1 2 0 1 0 0 181 34,011 0.53%
16 testicular 0 0 0 0 0 0 0 0 0 0 4,024 0.00%
17 throat 0 0 0 0 0 0 0 0 0 0 43 0.00%
18 thyroid 0 0 1 0 0 2 1 0 0 5 10,433 0.05%
19 tongue 0 0 0 0 0 0 0 0 0 0 802 0.00%
20 uterine 0 0 0 0 0 0 0 0 0 1 2,041 0.05%
21 uterine cervical 0 0 1 1 0 0 0 0 0 2 815 0.25%

6. Major country (affiliation) of the first author >
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